Functional Effects of the Coexistence of Hb-A with High Oxygen Affinity Hemoglobins

In carriers of abnormal haemoglobins with increased oxygen affinity, polyglobulia is the only possible functional compensation for tissue hypoxia.However, this adaptation is reduced if some Hb-A is used to synthesize hybrid haemoglobins of the type a2bAbX (heterotetramers). In fact, they display in...

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Bibliographic Details
Main Authors: G. Ricco, O. David, G. Ivaldi, M. Girotti, E. Rabino Massa
Format: Article
Language:English
Published: PAGEPress Publications 2003-12-01
Series:Journal of Biological Research
Online Access:https://www.pagepressjournals.org/index.php/jbr/article/view/10560