The recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters

Abstract The anti-inflammatory effects of the plant protease inhibitor BbCI (Bauhinia bauhinioides cruzipain inhibitor), which blocks elastase, cathepsin G, and L, and proteinase 3 has been demonstrated. Here, we investigated the recombinant rBbCI-His(6) (containing a histidine tail) in an experimen...

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Bibliographic Details
Main Authors: Cleide Oliveira, Mayara Vioto Valois, Tatiana Fontes Ottaiano, Antonio Miranda, Daiane Hansen, Misako Uemura Sampaio, Maria Luiza Vilela Oliva, Francisco Humberto de Abreu Maffei
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92745-4