The effect of immunomodulatory drugs on aortic stenosis: a Mendelian randomisation analysis

Abstract There are currently no approved pharmacological treatment options for aortic stenosis (AS), and there are limited identified drug targets for this chronic condition. It remains unclear whether inflammation plays a role in AS pathogenesis and whether immunomodulation could become a therapeut...

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Bibliographic Details
Main Authors: Jonathan L. Ciofani, Daniel Han, Milad Nazarzadeh, Usaid K. Allahwala, Giovanni Luigi De Maria, Adrian P. Banning, Ravinay Bhindi, Kazem Rahimi
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44387-x