Case Report: Rare <i>IKZF1</i> Gene Fusions Identified in Neonate with Congenital <i>KMT2A</i>-Rearranged Acute Lymphoblastic Leukemia

Case Report: Rare <i>IKZF1</i> Gene Fusions Identified in Neonate with Congenital <i>KMT2A</i>-Rearranged Acute Lymphoblastic Leukemia

Chromosomal rearrangements involving the <i>KMT2A</i> gene occur frequently in acute lymphoblastic leukaemia (ALL). <i>KMT2A</i>-rearranged ALL (<i>KMT2Ar</i> ALL) has poor long-term survival rates and is the most common ALL subtype in infants less than 1 year of...

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Bibliographic Details
Main Authors: Laura N. Eadie, Jacqueline A. Rehn, James Breen, Michael P. Osborn, Sophie Jessop, Charlotte E. J. Downes, Susan L. Heatley, Barbara J. McClure, David T. Yeung, Tamas Revesz, Benjamin Saxon, Deborah L. White
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Genes
Subjects:
congenital acute lymphoblastic leukemia
infant ALL
<i>KMT2A</i>-rearranged ALL
case report
chromosomal abnormalities
fusion gene
Online Access:https://www.mdpi.com/2073-4425/14/2/264

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https://www.mdpi.com/2073-4425/14/2/264

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