Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study

<p>Abstract</p> <p>Background</p> <p>Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. Pharmacokinetic studies have been based on analy...

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Bibliographic Details
Main Authors: Sørensen Olaf, Andersen Anders, Olsen Harald, Alexandr Kristian, Ekstrøm Per Olaf, Giercksky Karl-Erik, Flatmark Kjersti
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/469