Anti-Virulence Properties of Plant Species: Correlation between In Vitro Activity and Efficacy in a Murine Model of Bacterial Infection

Anti-Virulence Properties of Plant Species: Correlation between In Vitro Activity and Efficacy in a Murine Model of Bacterial Infection

Several plant extracts exhibit anti-virulence properties due to the interruption of bacterial quorum sensing (QS). However, studies on their effects at the preclinical level are scarce. Here, we used a murine model of abscess/necrosis induced by <i>Pseudomonas aeruginosa</i> to evaluate...

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Bibliographic Details
Main Authors: José Luis Díaz-Núñez, Macrina Pérez-López, Norma Espinosa, Nayelli Campos-Hernández, Rodolfo García-Contreras, Miguel Díaz-Guerrero, Humberto Cortes-López, Monserrat Vázquez-Sánchez, Héctor Quezada, Mariano Martínez-Vázquez, Ramón Marcos Soto-Hernández, Mireya Burgos-Hernández, Bertha González-Pedrajo, Israel Castillo-Juárez
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Microorganisms
Subjects:
cutaneous infection model
type III secretion system
quorum sensing
<i>Chromobacterium violaceum</i>
<i>Pseudomonas aeruginosa</i>
<i>Diphysa americana</i>
Online Access:https://www.mdpi.com/2076-2607/9/12/2424

Internet

https://www.mdpi.com/2076-2607/9/12/2424

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