Estimating time-varying exposure-outcome associations using case-control data: logistic and case-cohort analyses

Estimating time-varying exposure-outcome associations using case-control data: logistic and case-cohort analyses

Abstract Background Traditional analyses of standard case-control studies using logistic regression do not allow estimation of time-varying associations between exposures and the outcome. We present two approaches which allow this. The motivation is a study of vaccine efficacy as a function of time...

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Bibliographic Details
Main Authors: Ruth H. Keogh, Punam Mangtani, Laura Rodrigues, Patrick Nguipdop Djomo
Format: Article
Language:English
Published: BMC 2016-01-01
Series:BMC Medical Research Methodology
Subjects:
Case-control study
Case-cohort study
Cox proportional hazards model
Logistic regression
Time-varying association
Vaccine efficacy
Online Access:http://link.springer.com/article/10.1186/s12874-015-0104-0

Internet

http://link.springer.com/article/10.1186/s12874-015-0104-0

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