Systemic and microvascular comparison of Lactated Ringer’s solution, VIR-HBOC, and alpha-alpha crosslinked haemoglobin-based oxygen carrier in a rat 10% topload model

Systemic and microvascular comparison of Lactated Ringer’s solution, VIR-HBOC, and alpha-alpha crosslinked haemoglobin-based oxygen carrier in a rat 10% topload model

AbstractMedical support for traumatic haemorrhage is lacking for far-forward combat units. VIR-HBOC (haemoglobin-based oxygen carrier) is a novel biological therapeutic under development as a field-stable resuscitation fluid. HBOCs have a long history of complications, chief among them is vasoconstr...

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Bibliographic Details
Main Authors: Bjorn K. Song, W. Richard Light, Kim D. Vandegriff, Joe Tucker, William H. Nugent
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Microcirculation
haemoglobin-based oxygen carrier
hyperpolymerized haemoglobin
phosphorescence quenching microscopy
interstitial oxygenation
topload
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2020.1809441

Internet

https://www.tandfonline.com/doi/10.1080/21691401.2020.1809441

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