TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness

TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness

The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been reported to determine cell permissivity to HIV-1 fusion and infection acting on tubulin-deacetylase HDAC6. Here, we studied the functional involvem...

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Bibliographic Details
Main Authors: Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Judith Estévez-Herrera, Jonay García-Luis, Rodrigo Trujillo-González, Agustín Valenzuela-Fernández
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
TARDBP/TDP-43
HDAC6
autophagy
viral production
HIV-1 infection capacity
Online Access:https://www.mdpi.com/1422-0067/24/8/7658

Internet

https://www.mdpi.com/1422-0067/24/8/7658

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