Distinctive interactomes of RNA polymerase II phosphorylation during different stages of transcription

Summary: During eukaryotic transcription, RNA polymerase II undergoes dynamic post-translational modifications on the C-terminal domain (CTD) of the largest subunit, generating an information-rich PTM landscape that transcriptional regulators bind. The phosphorylation of Ser5 and Ser2 of CTD heptad...

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Bibliographic Details
Main Authors: Rosamaria Y. Moreno, Kyle J. Juetten, Svetlana B. Panina, Jamie P. Butalewicz, Brendan M. Floyd, Mukesh Kumar Venkat Ramani, Edward M. Marcotte, Jennifer S. Brodbelt, Y. Jessie Zhang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223016589