Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages

In the lungs, macrophages constitute the first line of defense against pathogens and foreign bodies and play a fundamental role in maintaining tissue homeostasis. Activated macrophages show altered immunometabolism and metabolic changes governing immune effector mechanisms, such as cytokine secretio...

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Bibliographic Details
Main Authors: Antonella Marrocco, Luis A. Ortiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.936167/full