Longitudinal functional imaging of VIP interneurons reveals sup-population specific effects of stroke that are rescued with chemogenetic therapy

Stroke profoundly disrupts cortical excitability which impedes recovery, but how stroke affects inhibitory interneurons is poorly understood. Here, the authors show that functional impairments after stroke are associated with the disruption of a highly active subpopulation of interneurons expressing...

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Bibliographic Details
Main Authors: Mohamad Motaharinia, Kim Gerrow, Roobina Boghozian, Emily White, Sun-Eui Choi, Kerry R. Delaney, Craig E. Brown
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26405-6