Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

Abstract Background Age > 65 years is a key risk factor for poor outcomes after human influenza infection. Specifically, in addition to respiratory disease, non-neurotropic influenza A virus (IAV) causes neuro-cognitive complications, e.g. new onset depression and increases the risk of dementia a...

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Bibliographic Details
Main Authors: Wenxin Wu, Jeremy S. Alexander, J. Leland Booth, Craig A. Miller, Jordan P. Metcalf, Douglas A. Drevets
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Immunity & Ageing
Subjects:
Influenza virus
Aging
Brain
Lung
CNS
Neuroinflammation
Online Access:https://doi.org/10.1186/s12979-024-00447-y

Internet

https://doi.org/10.1186/s12979-024-00447-y

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