Unravelling the physiological roles of mazEF toxin–antitoxin system on clinical MRSA strain by CRISPR RNA-guided cytidine deaminase

Unravelling the physiological roles of mazEF toxin–antitoxin system on clinical MRSA strain by CRISPR RNA-guided cytidine deaminase

Abstract Background Curiosity on toxin–antitoxin modules has increased intensely over recent years as it is ubiquitously present in many bacterial genomes, including pathogens like Methicillin-resistant Staphylococcus aureus (MRSA). Several cellular functions of TA systems have been proposed however...

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Bibliographic Details
Main Authors: Sonia Jain, Arghya Bhowmick, Bohyun Jeong, Taeok Bae, Abhrajyoti Ghosh
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Biomedical Science
Subjects:
MRSA
Biofilm
Antibiotic resistance
Virulence
CRISPR–Cas9
Toxin–antitoxin
Online Access:https://doi.org/10.1186/s12929-022-00810-5

Internet

https://doi.org/10.1186/s12929-022-00810-5

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