Adipolin protects against renal injury via PPARα-dependent reduction of inflammasome activation

Adipolin protects against renal injury via PPARα-dependent reduction of inflammasome activation

Summary: Although chronic kidney disease (CKD) is a major health problem worldwide, its underlining mechanism is incompletely understood. We previously identified adipolin as an adipokine which provides benefits for cardiometabolic diseases. Here, we investigated the role of adipolin in the developm...

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Bibliographic Details
Main Authors: Lixin Fang, Koji Ohashi, Satoko Hayakawa, Hayato Ogawa, Naoya Otaka, Hiroshi Kawanishi, Tomonobu Takikawa, Yuta Ozaki, Kunihiko Takahara, Minako Tatsumi, Mikito Takefuji, Yuuki Shimizu, Yasuko K. Bando, Yuya Fujishima, Norikazu Maeda, Iichiro Shimomura, Toyoaki Murohara, Noriyuki Ouchi
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006685

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http://www.sciencedirect.com/science/article/pii/S2589004223006685

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