The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages

The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages

Physiological selenium (Se) levels counteract excessive inflammation, with selenoproteins shaping the immunoregulatory cytokine and lipid mediator profile. How exactly differentiation of monocytes into macrophages influences the expression of the selenoproteome in concert with the Se supply remains...

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Bibliographic Details
Main Authors: Theresa Wolfram, Leonie M. Weidenbach, Johanna Adolf, Maria Schwarz, Patrick Schädel, André Gollowitzer, Oliver Werz, Andreas Koeberle, Anna P. Kipp, Solveigh C. Koeberle
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
selenium
selenoprotein
macrophage
differentiation
inflammation
redox signaling
Online Access:https://www.mdpi.com/1422-0067/22/20/11060

Internet

https://www.mdpi.com/1422-0067/22/20/11060

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