An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer

An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer

Introduction: POLD2 is an indispensable subunit of DNA polymerase δ, which is responsible for the synthesis of the backward accompanying strand in eukaryotic organisms. Current studies have found an association between POLD2 and the development of a variety of cancers. However, its value in cancer i...

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Bibliographic Details
Main Authors: Fengyun Cong, Junxian Long, Jun Liu, Zhixiang Deng, Binli Yan, Cao Liang, Xiaoliang Huang, Jinxin Liu, Weizhong Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
pan-cancer
POLD2
immune checkpoints
immune infiltration
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.877468/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.877468/full

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