A water-soluble caveolin-1 peptide inhibits psoriasis-like skin inflammation by suppressing cytokine production and angiogenesis

A water-soluble caveolin-1 peptide inhibits psoriasis-like skin inflammation by suppressing cytokine production and angiogenesis

Abstract The plasma membrane protein caveolin-1 (CAV-1) regulates signaling by inhibiting a wide range of kinases and other enzymes. Our previous study demonstrated that the downregulation of CAV-1 in psoriatic epidermal cells contributes to inflammation by enhancing JAK/STAT signaling, cell prolife...

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Bibliographic Details
Main Authors: Chika Asai, Naoko Takamura, Tomoya Watanabe, Miho Asami, Noriko Ikeda, Charles F. Reese, Stanley Hoffman, Yukie Yamaguchi
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Scientific Reports
Subjects:
Psoriasis
Skin inflammation
Caveolin-1
CSD peptide
water-soluble subregions
Online Access:https://doi.org/10.1038/s41598-024-71350-1

Internet

https://doi.org/10.1038/s41598-024-71350-1

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