Effect of Conjugation of Activated Glutaraldehyde-Nanochitosan with L-Asparaginase as an Anti Cancer Enzyme on its Stability and Physicochemical Properties

Effect of Conjugation of Activated Glutaraldehyde-Nanochitosan with L-Asparaginase as an Anti Cancer Enzyme on its Stability and Physicochemical Properties

Introduction: The bacterial Asparaginase is used in the treatment of asparagine-dependent tumors, particularly lymphatic sarcoma and acute lymphoblastic leukemia. However, the instability of the enzyme increases the number of injections that are accompanied by high immune responses. The aim of this...

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Bibliographic Details
Main Authors: Nabiallah khoonmirzaie, Mohammad Razi Jalali, Ali Sahriari, Mohammad Reza Tabandeh
Format: Article
Language:fas
Published: Shahid Sadoughi University of Medical Sciences 2020-05-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Subjects:
l-asparaginase
conjugation
nanochitosan
glutaraldehyde
physicochemical properties
Online Access:http://jssu.ssu.ac.ir/article-1-4869-en.html

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http://jssu.ssu.ac.ir/article-1-4869-en.html

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