L1cam acts as a modifier gene during enteric nervous system development

The enteric nervous system is derived from neural crest cells that migrate from the caudal hindbrain and colonise the gut. Failure of neural crest cells to fully colonise the gut results in an “aganglionic zone” that lacks a functional enteric nervous system over a variable length of the distal bowe...

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Bibliographic Details
Main Authors: Adam S. Wallace, Claudia Schmidt, Melitta Schachner, Michael Wegner, Richard B. Anderson
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110002615