L1cam acts as a modifier gene during enteric nervous system development
The enteric nervous system is derived from neural crest cells that migrate from the caudal hindbrain and colonise the gut. Failure of neural crest cells to fully colonise the gut results in an “aganglionic zone” that lacks a functional enteric nervous system over a variable length of the distal bowe...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-12-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996110002615 |