Group A Streptococcus Prevents Mast Cell Degranulation to Promote Extracellular Trap Formation

The resurgence of Group A Streptococcus (GAS) infections in the past two decades has been a rising major public health concern. Due to a large number of GAS infections occurring in the skin, mast cells (MCs), innate immune cells known to localize to the dermis, could play an important role in contro...

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Bibliographic Details
Main Authors: Mary Clark, Jessica Kim, Neelou Etesami, Jacqueline Shimamoto, Ryan V. Whalen, Gary Martin, Cheryl Y. M. Okumura
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00327/full