Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation

<p>Abstract</p> <p>Background</p> <p>DNA methylation plays a vital role in normal cellular function, with aberrant methylation signatures being implicated in a growing number of human pathologies and complex human traits. Methods based on the modification of genomic DNA...

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Bibliographic Details
Main Authors: Docherty Sophia J, Davis Oliver SP, Haworth Claire MA, Plomin Robert, Mill Jonathan
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/2/1/3