Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials

Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials

Multimodality treatment is a standard of care for LARC, but the optimal sequencing of the treatment modalities remains unclear. Several randomized clinical trials (RCTs) compared total neoadjuvant treatment (TNT) vs. standard neoadjuvant chemoradiotherapy (CRT) with inconsistent results. A systemati...

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Bibliographic Details
Main Authors: Maria C. Riesco-Martinez, Carlos Fernandez-Martos, Cristina Gravalos-Castro, Paula Espinosa-Olarte, Anna La Salvia, Luis Robles-Diaz, Andrea Modrego-Sanchez, Rocio Garcia-Carbonero
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
meta-analysis
rectal cancer
neoadjuvant therapy
chemotherapy
treatment
Online Access:https://www.mdpi.com/2072-6694/12/12/3655

Internet

https://www.mdpi.com/2072-6694/12/12/3655

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