Calcium signaling in live cells on elastic gels under mechanical vibration at subcellular levels.

A new device was designed to generate a localized mechanical vibration of flexible gels where human umbilical vein endothelial cells (HUVECs) were cultured to mechanically stimulate these cells at subcellular locations. A Fluorescence Resonance Energy Transfer (FRET)-based calcium biosensor (an impr...

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Bibliographic Details
Main Authors: Wagner Shin Nishitani, Taher A Saif, Yingxiao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203865?pdf=render