Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation
Tetrahydrobiopterin (BH4) is a major endogenous vasoprotective agent that improves endothelial function by increasing nitric oxide (NO) synthesis and scavenging of superoxide and peroxynitrite. Accordingly, administration of BH4 is considered as a promising therapy of cardiovascular diseases associa...
Główni autorzy: | , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
De Gruyter
2013-06-01
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Seria: | Pteridines |
Hasła przedmiotowe: | |
Dostęp online: | https://doi.org/10.1515/pterid-2013-0015 |