Enhancement of internalization of diphtheria toxin recombinant fragments in sensitive cells mediated by toxin’s T-domain
Subunit B of diphtheria toxin (DT) and its R-domain differ by the presence of T-domain. The aim of the present work was to analyze the interaction of these toxin fragments with mammalian cells in order to evaluate the T-domain’s influence on endocytosis in resistant cells. Internalization of recombi...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2017-10-01
|
Series: | The Ukrainian Biochemical Journal |
Subjects: | |
Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2017/10/Manoilov_5-17.pdf |