Enantiomeric Resolution of Drugs and Metabolites in Polysaccharide- and Protein-Based Chiral Stationary Phases

Enantiomeric Resolution of Drugs and Metabolites in Polysaccharide- and Protein-Based Chiral Stationary Phases

Several chiral stationary phases based on polysaccharide derivatives and proteins were evaluated for the resolution of some chiral drugs and their metabolites. The polysaccharide-based stationary phases CHIRALCEL OD-H, CHIRALCEL OB-H, CHIRALCEL OJ, CHIRALPAK AD and CHIRALPAK AS were evaluated under...

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Bibliographic Details
Main Authors: Bonato Pierina S., Bortocan Renato, Gaitani Cristiane M., Paias Fernanda O., Iha Maria H., Lima Rodrigo P.
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2002-01-01
Series:Journal of the Brazilian Chemical Society
Subjects:
polysaccharide-based stationary phases
protein- based stationary phases
drugs
metabolites
enantioselective analysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000200010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000200010

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