Cytoprotective Role of Heme Oxygenase-1 in Cancer Chemoresistance: Focus on Antioxidant, Antiapoptotic, and Pro-Autophagy Properties

Chemoresistance remains the foremost challenge in cancer therapy. Targeting reactive oxygen species (ROS) manipulation is a promising strategy in cancer treatment since tumor cells present high levels of intracellular ROS, which makes them more vulnerable to further ROS elevation than normal cells....

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Bibliographic Details
Main Authors: Huan Wang, Qi Cheng, Lingjie Bao, Mingqing Li, Kaikai Chang, Xiaofang Yi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/6/1217