Lubricant-entrenched slippery surface-based nanocarriers to avoid macrophage uptake and improve drug utilization

Lubricant-entrenched slippery surface-based nanocarriers to avoid macrophage uptake and improve drug utilization

Introduction: Reducing the protein adsorption of nanoparticles (NPs) as drug carriers to slow their rapid clearance by macrophages uptake is a critical challenge for NPs clinical translational applications. Despite extensive research efforts to inhibit cellular uptake, including covering biological...

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Bibliographic Details
Main Authors: Chengduan Yang, Jianming Feng, Ziqi Liu, Juan Jiang, Xiafeng Wang, Cheng Yang, Hui-jiuan Chen, Xi Xie, Liru Shang, Ji Wang, Zhenwei Peng
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Advanced Research
Subjects:
Nanocarriers
Lubricant-entrenched slippery surfaces
Anti-adhesion of proteins
Anti-uptake of macrophage
Improving drug utilization
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222001965

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http://www.sciencedirect.com/science/article/pii/S2090123222001965

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