NSAIDs modulate clonal evolution in Barrett's esophagus.

NSAIDs modulate clonal evolution in Barrett's esophagus.

Cancer is considered an outcome of decades-long clonal evolution fueled by acquisition of somatic genomic abnormalities (SGAs). Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce cancer risk, including risk of progression from Barrett's esophagus (BE) to esophageal adenoca...

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Bibliographic Details
Main Authors: Rumen L Kostadinov, Mary K Kuhner, Xiaohong Li, Carissa A Sanchez, Patricia C Galipeau, Thomas G Paulson, Cassandra L Sather, Amitabh Srivastava, Robert D Odze, Patricia L Blount, Thomas L Vaughan, Brian J Reid, Carlo C Maley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3681672?pdf=render

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http://europepmc.org/articles/PMC3681672?pdf=render

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