NSAIDs modulate clonal evolution in Barrett's esophagus.

NSAIDs modulate clonal evolution in Barrett's esophagus.

Cancer is considered an outcome of decades-long clonal evolution fueled by acquisition of somatic genomic abnormalities (SGAs). Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce cancer risk, including risk of progression from Barrett's esophagus (BE) to esophageal adenoca...

Full description

Bibliographic Details
Main Authors:	Rumen L Kostadinov, Mary K Kuhner, Xiaohong Li, Carissa A Sanchez, Patricia C Galipeau, Thomas G Paulson, Cassandra L Sather, Amitabh Srivastava, Robert D Odze, Patricia L Blount, Thomas L Vaughan, Brian J Reid, Carlo C Maley
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-06-01
Series:	PLoS Genetics
Online Access:	http://europepmc.org/articles/PMC3681672?pdf=render

Similar Items

NSAID use and somatic exomic mutations in Barrett’s esophagus
by: Patricia C. Galipeau, et al.
Published: (2018-02-01)

Correction to: NSAID use and somatic exomic mutations in Barrett’s esophagus
by: Patricia C. Galipeau, et al.
Published: (2019-03-01)

p16 mutation spectrum in the premalignant condition Barrett's esophagus.
by: Thomas G Paulson, et al.
Published: (2008-01-01)

The role of tobacco, alcohol, and obesity in neoplastic progression to esophageal adenocarcinoma: a prospective study of Barrett's esophagus.
by: Sheetal Hardikar, et al.
Published: (2013-01-01)

NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma.
by: Patricia C Galipeau, et al.
Published: (2007-02-01)

High Goblet Cell Count Is Inversely Associated with Ploidy Abnormalities and Risk of Adenocarcinoma in Barrett's Esophagus.
by: Amitabh Srivastava, et al.
Published: (2015-01-01)

Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels
by: Pierre Martinez, et al.
Published: (2018-02-01)

Somatic whole genome dynamics of precancer in Barrett’s esophagus reveals features associated with disease progression
by: Thomas G. Paulson, et al.
Published: (2022-04-01)

Mapping clonality in individual glands in human Barrett's esophagus
by: Leedham, S, et al.
Published: (2007)

Bacterial Composition of the Human Upper Gastrointestinal Tract Microbiome Is Dynamic and Associated with Genomic Instability in a Barrett's Esophagus Cohort.
by: Alevtina Gall, et al.
Published: (2015-01-01)

Warburg and Crabtree effects in premalignant Barrett's esophagus cell lines with active mitochondria.
by: Martin T Suchorolski, et al.
Published: (2013-01-01)

Barrett's esophagus.
by: Bird-Lieberman, E, et al.
Published: (2008)

Barrett's Esophagus
by: Yong Kang Lee
Published: (2022-09-01)

Esófago de Barrett Barrett´s esophagus
by: José Miguel Esteban López-Jamar, et al.
Published: (2012-08-01)

TissueCypher Barrett’s esophagus assay impacts clinical decisions in the management of patients with Barrett’s esophagus
by: David L. Diehl, et al.
Published: (2021-02-01)

Paired exome analysis of Barrett's esophagus and adenocarcinoma
by: Stachler, Matthew D, et al.
Published: (2016)

Paired exome analysis of Barrett's esophagus and adenocarcinoma
by: Stachler, Matthew D, et al.
Published: (2017)

Squamous cell carcinoma in Barrett’s esophagus
by: Esteban Trakál, et al.
Published: (2014-01-01)

Developments in Barrett's Esophagus
by: Richard E. Sampliner
Published: (2006-01-01)

LAPAROSCOPIC FUNDOPLICATION IN THE TREATMENT OF BARRETT’S ESOPHAGUS
by: A. S. Allakhverdyan, et al.
Published: (2016-02-01)

Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants.
by: Yumie Takata, et al.
Published: (2012-01-01)

Clinical and morphological analysis of dysplasia in Barrett's esophagus and columnar-lined esophagus
by: L. M. Mikhaleva, et al.
Published: (2020-07-01)

Bulk Genotyping of Biopsies Can Create Spurious Evidence for Hetereogeneity in Mutation Content.
by: Rumen Kostadinov, et al.
Published: (2016-04-01)

Barrett´s esophagus: a review Esofago de Barrett
by: C. Ciriza-de-los-Ríos
Published: (2010-04-01)

Application of biomarkers in cancer risk management: evaluation from stochastic clonal evolutionary and dynamic system optimization points of view.
by: Xiaohong Li, et al.
Published: (2011-02-01)

Multimodal integration for Barrett’s esophagus
by: Shubin Liu, et al.
Published: (2024-02-01)

Barrett’s Esophagus: An Updated Review
by: Peter M. Stawinski, et al.
Published: (2023-01-01)

Diagnosis and Management of Barrett’s Esophagus
by: Maja Mejza, et al.
Published: (2023-03-01)

Educational Case: Barrett Esophagus
by: Mackinzie McDaniel BS, et al.
Published: (2019-05-01)

Is It Barrett's Esophagus or Gastric Heterotopia
by: Zeynel Mungan
Published: (2014-10-01)

Barrett’s Esophagus and Intestinal Metaplasia
by: Lu Zhang, et al.
Published: (2021-06-01)

‘Artificial intelligence in Barrett’s Esophagus’
by: Nour Hamade, et al.
Published: (2021-10-01)

Endoscopic therapy for Barrett′s esophagus
by: Nicholas J. Shaheen
Published: (2012-01-01)

Barrett's esophagus: The advocacy for ESD
by: Pierre H. Deprez
Published: (2016-06-01)

Recurrent Barrett's esophagus and adenocarcinoma after esophagectomy
by: Hemminger Lois L, et al.
Published: (2004-08-01)

Barrett’s Esophagus in Romania: what do we know?
by: Piloiu Claudia, et al.
Published: (2020-09-01)

A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.
by: Linda C Cummings, et al.
Published: (2017-01-01)

Clinic-morphological diagnosis of Barrett’s esophagus
by: O. G. Кuryk, et al.
Published: (2018-07-01)

Chemoprevention in Barrett’s esophagus and esophageal adenocarcinoma
by: Motasem Alkhayyat, et al.
Published: (2021-08-01)

Fístula esófago pleural en esófago de Barrett Esophago-pleural fistula in Barrett's esophagus
by: M. Morán Ortiz de Solórzano, et al.
Published: (2009-04-01)