Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome

Abstract Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be associated with significant metabolic and bioenergetic alterations. However, the relevant scientific literature has not yet been systematically reviewed. The aim of the current study was to conduct a m...

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Bibliographic Details
Main Authors: Laszlo Pecze, Elisa B. Randi, Csaba Szabo
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10020-020-00225-8