An Approach to Identify HLA Class II Immunogenic Epitopes in the Greek Population through Machine Learning Algorithms

An Approach to Identify HLA Class II Immunogenic Epitopes in the Greek Population through Machine Learning Algorithms

Current pre-transplantation routine matching involves serum anti-HLA antibodies quantification but cannot always preclude unfavorable graft outcomes. Epitope-based matching is proposed as a more precise approach, but to date no epitope-matching algorithm provides a satisfactory predictive tool for t...

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Bibliographic Details
Main Authors: Asimina Fylaktou, Georgios Lioulios, Katerina Tarassi, Alexandra Siorenta, George Ch Petasis, Demetris Gerogiannis, Ioannis Theodorou, Aliki G. Iniotaki, Angeliki G. Vittoraki
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Clinical Medicine
Subjects:
machine learning
epitope matching
eplets
anti-HLA class II responses
alloimmune response
transplantation
Online Access:https://www.mdpi.com/2077-0383/11/23/7046

Internet

https://www.mdpi.com/2077-0383/11/23/7046

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