Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases

Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases

Integrases of different retroviruses assemble as functional complexes with varying multimers of the protein. Retroviral integrases require a divalent metal cation to perform one-step transesterification catalysis. Tetrameric prototype foamy virus (PFV) intasomes assembled from purified integrase and...

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Bibliographic Details
Main Authors: Anthony J. Rabe, Yow Yong Tan, Ross C. Larue, Kristine E. Yoder
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
integrase
retrovirus
prototype foamy virus
divalent cation
Online Access:https://www.mdpi.com/2218-273X/11/12/1910

Internet

https://www.mdpi.com/2218-273X/11/12/1910

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