FREQUENCY AND ANALYSIS OF THE EPIDEMIOLOGICAL PROFILE OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA IN PATIENTS FROM A BRAZILIAN DIAGNOSTIC CENTER
Paroxysmal Nocturnal Hemoglobinuria (PNH) is a disease resulting from a somatic mutation in the PIG-A gene (phosphatidylinositol glycan class A), which encodes an anchor enzyme called GPI (glycosyl-phosphatidylinositol). The alteration in the synthesis of this enzyme leads to partial or total defici...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923002766 |