NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

Summary: Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like Receptor 7 (TLR7) signalling in dendritic cells (DC...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J. de Jesus, Ananya Vadlakonda, Joshua T. Centore, Alexis D. Griffith, Bethany Rohr, Thomas S. McCormick, Kevin D. Cooper, Parameswaran Ramakrishnan
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2024-12-01
Schriftenreihe:EBioMedicine
Schlagworte:
TLR7
NF-κB c-Rel
Inflammation
Psoriasis
Transcription
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2352396424004882

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http://www.sciencedirect.com/science/article/pii/S2352396424004882

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