Chronic myocardial and coronary arterial effects of intracoronary supersaturated oxygen therapy in swine with normal and ischemic-reperfused myocardium

Abstract The study assessed chronic myocardial, coronary and systemic effects of intracoronary supersaturated oxygen (SSO2) therapy. Left anterior descending coronary arteries of 40 swine were stented and randomized to 90-min selective intracoronary infusion of SSO2 (pO2 760–1000 mmHg) or normoxemic...

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Main Authors: Grzegorz L. Kaluza, Jeffrey L. Creech, Ariel Furer, Maxwell E. Afari, Krzysztof Milewski, Geng-Hua Yi, Yanping Cheng, Gerard B. Conditt, Jenn C. McGregor, Donald Blum, Serge D. Rousselle, Juan F. Granada, Daniel Burkhoff
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09776-8