Dynamics of the Tumor Immune Microenvironment during Neoadjuvant Chemotherapy of High-Grade Serous Ovarian Cancer

Dynamics of the Tumor Immune Microenvironment during Neoadjuvant Chemotherapy of High-Grade Serous Ovarian Cancer

The dynamic changes in the tumor immune microenvironment (TIME) triggered by neoadjuvant chemotherapy (NAC) have not been clearly defined in advanced-stage ovarian cancer. We analyzed the immunologic changes induced by NAC to correlate them with clinical outcomes. We compared the changes in the immu...

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Bibliographic Details
Main Authors: Yong Jae Lee, Ha Young Woo, Yoo-Na Kim, Junsik Park, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim, Young Tae Kim, Eunhyang Park, Je-Gun Joung, Jung-Yun Lee
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
tumor immune microenvironment
neoadjuvant chemotherapy
tumor-infiltrating lymphocytes
high grade serous ovarian cancer
immune checkpoint inhibitors
Online Access:https://www.mdpi.com/2072-6694/14/9/2308

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https://www.mdpi.com/2072-6694/14/9/2308

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