Toll-Like Receptor 3 Is Involved in Detection of Enterovirus A71 Infection and Targeted by Viral 2A Protease

Toll-Like Receptor 3 Is Involved in Detection of Enterovirus A71 Infection and Targeted by Viral 2A Protease

Enterovirus A71 (EV-A71) has emerged as a major pathogen causing hand, foot, and mouth disease, as well as neurological disorders. The host immune response affects the outcomes of EV-A71 infection, leading to either resolution or disease progression. However, the mechanisms of how the mammalian inna...

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Bibliographic Details
Main Authors: Kuan-Ru Chen, Chun-Keung Yu, Szu-Hao Kung, Shun-Hua Chen, Chuan-Fa Chang, Tzu-Chuan Ho, Yi-Ping Lee, Hung-Chuan Chang, Lan-Yin Huang, Shih-Yen Lo, Jui-Chung Chang, Pin Ling
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
Enterovirus 71
Toll-like receptor 3
innate immune system
EV-A71 protease 2A
Type I IFN
Online Access:https://www.mdpi.com/1999-4915/10/12/689

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https://www.mdpi.com/1999-4915/10/12/689

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