Concurrent Quinidine and Phenobarbital in the Treatment of a Patient with 2 KCNT1 Mutations

ABSTRACT: Epilepsy of infancy with migrating focal seizures is a devastating pediatric neurologic disorder that often results in treatment-resistant seizure activity and developmental delay. The condition has been associated with mutations in the KCNT1 gene that cause a gain of function in neuronal...

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Bibliographic Details
Main Authors: Camerin C. Passey, PharmD, MBA, John Erramouspe, PharmD, MS, Peter Castellanos, MD, Elizabeth C. O'Donnell, MD, FAAP, David M. Denton, MD
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Current Therapeutic Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X18300626