Comprehensive molecular analysis of immortalization hallmarks in thyroid cancer reveals new prognostic markers

Comprehensive molecular analysis of immortalization hallmarks in thyroid cancer reveals new prognostic markers

Background Comprehensive molecular studies on tumours are needed to delineate immortalization process steps and identify sensitive prognostic biomarkers in thyroid cancer. Methods and Results In this study, we extensively characterize telomere‐related alterations in a series of 106 thyroid tumours w...

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Bibliographic Details
Main Authors: Cristina Montero‐Conde, Luis Javier Leandro‐García, Ángel M. Martínez‐Montes, Paula Martínez, Francisco J. Moya, Rocío Letón, Eduardo Gil, Natalia Martínez‐Puente, Sonsoles Guadalix, Maria Currás‐Freixes, Laura García‐Tobar, Carles Zafon, Mireia Jordà, Garcilaso Riesco‐Eizaguirre, Patricia González‐García, María Monteagudo, Rafael Torres‐Pérez, Veronika Mancikova, Sergio Ruiz‐Llorente, Manuel Pérez‐Martínez, Guillermo Pita, Juan Carlos Galofré, Anna Gonzalez‐Neira, Alberto Cascón, Cristina Rodríguez‐Antona, Diego Megías, María A. Blasco, Eduardo Caleiras, Sandra Rodríguez‐Perales, Mercedes Robledo
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Clinical and Translational Medicine
Subjects:
5p‐end FISH
subtelomeric gene expression
telomere shortening
TERC
TERT promoter methylation
TERT promoter mutation
Online Access:https://doi.org/10.1002/ctm2.1001

Internet

https://doi.org/10.1002/ctm2.1001

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