High throughput screening system for engineered cardiac tissues

Introduction: Three dimensional engineered cardiac tissues (3D ECTs) have become indispensable as in vitro models to assess drug cardiotoxicity, a leading cause of failure in pharmaceutical development. A current bottleneck is the relatively low throughput of assays that measure spontaneous contract...

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Bibliographic Details
Main Authors: Marshall S. Ma, Subramanian Sundaram, Lihua Lou, Arvind Agarwal, Christopher S. Chen, Thomas G. Bifano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1177688/full