The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.

The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.

Multiple sclerosis (MS) is a T cell-driven autoimmune disease that attacks the myelin of the central nervous system (CNS) and currently has no cure. MS etiology is linked to both the gut flora and external environmental factors but this connection is not well understood. One immune system regulator...

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Bibliographic Details
Main Authors: Andrea R Merchak, Hannah J Cahill, Lucille C Brown, Ryan M Brown, Courtney Rivet-Noor, Rebecca M Beiter, Erica R Slogar, Deniz G Olgun, Alban Gaultier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002000

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https://doi.org/10.1371/journal.pbio.3002000

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