In silico studies on the interaction of four cytotoxic compounds with angiogenesis target protein HIF-1α and human androgen receptor and their ADMET properties

In silico studies on the interaction of four cytotoxic compounds with angiogenesis target protein HIF-1α and human androgen receptor and their ADMET properties

Abstract Background Cancer is a significant public health problem worldwide and constitutes the second leading cause of death after cardiovascular disease. This study was thus designed to identify new natural compounds from Malagasy medicinal plants traditionally used to treat cancer. Methods In sil...

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Bibliographic Details
Main Authors: Jean-Paul Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Aristote Matondo, Colette Masengo Ashande, Janvier Mukiza, Célestin Mudogo Nzanzu, Fatiany Pierre Ruphin, Robijaona Baholy, Pius T. Mpiana, Virima Mudogo
Format: Article
Language:English
Published: SpringerOpen 2022-04-01
Series:Bulletin of the National Research Centre
Subjects:
Evidence-based medicine
Structural molecular biology
Chemo-informatics
Cancer
Madagascar
Online Access:https://doi.org/10.1186/s42269-022-00793-1

Internet

https://doi.org/10.1186/s42269-022-00793-1

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