Using Topological Indices to Predict Anti-Alzheimer and Anti-Parasitic GSK-3 Inhibitors by Multi-Target QSAR in Silico Screening

Using Topological Indices to Predict Anti-Alzheimer and Anti-Parasitic GSK-3 Inhibitors by Multi-Target QSAR in Silico Screening

Plasmodium falciparum, Leishmania, Trypanosomes, are the causers of diseases such as malaria, leishmaniasis and African trypanosomiasis that nowadays are the most serious parasitic health problems worldwide. The great number of deaths and the few drugs available against these parasites, make necessa...

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Bibliographic Details
Main Authors: Generosa Gómez, Yagamare Fall, Isela García
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Molecules
Subjects:
glycogen synthase kinase-3 (GSK-3) inhibitors
Alzheimer’s disease
Plasmodium falciparum
Trypanosoma brucei
Leishmania
QSAR
Online Access:http://www.mdpi.com/1420-3049/15/8/5408/

Internet

http://www.mdpi.com/1420-3049/15/8/5408/

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