The ELG1 clamp loader plays a role in sister chromatid cohesion.

The ELG1 clamp loader plays a role in sister chromatid cohesion.

Mutations in the ELG1 gene of yeast lead to genomic instability, manifested in high levels of genetic recombination, chromosome loss, and gross chromosomal rearrangements. Elg1 shows similarity to the large subunit of the Replication Factor C clamp loader, and forms a RFC-like (RLC) complex in conju...

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Bibliographic Details
Main Authors: Oren Parnas, Adi Zipin-Roitman, Yuval Mazor, Batia Liefshitz, Shay Ben-Aroya, Martin Kupiec
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2676507?pdf=render

Internet

http://europepmc.org/articles/PMC2676507?pdf=render

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