Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis

Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis

Objective: Transformation of white into brown fat (“browning”) reduces obesity in many preclinical models and holds great promise as a therapeutic concept in metabolic disease. Vitamin A metabolites (retinoids) have been linked to thermogenic programming of adipose tissue; however, the physiologic i...

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Bibliographic Details
Main Authors: Anna Fenzl, Oana Cristina Kulterer, Katrin Spirk, Goran Mitulović, Rodrig Marculescu, Martin Bilban, Sabina Baumgartner-Parzer, Alexandra Kautzky-Willer, Lukas Kenner, Jorge Plutzky, Loredana Quadro, Florian W. Kiefer
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Brown adipose tissue
Thermogenesis
Browning
Adipocytes
Retinol binding protein
Retinoids
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301629

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http://www.sciencedirect.com/science/article/pii/S2212877820301629

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