Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B

Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B

Abstract Background Hepatitis B virus (HBV) infection is a public health problem that seriously threatens human health. This study aimed to investigate the clinical significance of glutathione peroxidase 4(GPX4) in the occurrence and development of chronic hepatitis B (CHB). Methods A total of 169 p...

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Bibliographic Details
Main Authors: Xing Su, Zhaohui Wang, Jihui Li, Shuai Gao, Yuchen Fan, Kai Wang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Virology Journal
Subjects:
Chronic hepatitis B
Glutathione peroxidase 4
STING
DNA methylation
Oxidative stress
Online Access:https://doi.org/10.1186/s12985-024-02346-6

Internet

https://doi.org/10.1186/s12985-024-02346-6

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