Perineuronal nets affect memory and learning after synapse withdrawal

Abstract Perineuronal nets (PNNs) enwrap mature neurons, playing a role in the control of plasticity and synapse dynamics. PNNs have been shown to have effects on memory formation, retention and extinction in a variety of animal models. It has been proposed that the cavities in PNNs, which contain s...

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Bibliographic Details
Main Authors: Jiri Ruzicka, Marketa Dalecka, Kristyna Safrankova, Diego Peretti, Pavla Jendelova, Jessica C. F. Kwok, James W. Fawcett
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02226-z