Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model

Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by deficits in social interaction and communication, and repetitive behaviors. In addition, co-morbidities such as gastro-intestinal problems have frequently been reported. Mutations and deletion of proteins of...

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Bibliographic Details
Main Authors: Ann Katrin Sauer, Juergen Bockmann, Konrad Steinestel, Tobias M. Boeckers, Andreas M. Grabrucker
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
microbiome
gut
ProSAP2
Phelan McDermid Syndrome
gut–brain interaction
leaky gut
IL-6
SHANK
Online Access:https://www.mdpi.com/1422-0067/20/9/2134

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https://www.mdpi.com/1422-0067/20/9/2134

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